یک مدل پویایی‌شناسی سیستم برای تنظیم تصمیم‌های موجودی در مولدهای رادیونوکلید

نوع مقاله: مقاله پژوهشی

نویسندگان

1 دانشکده مهندسی صنایع، دانشگاه علم و صنعت ایران تهران ـ ایران

2 دانشکده مهندسی صنایع، دانشگاه علم و صنعت ایران، صندوق پستی، تهران ـ ایران

3 گروه پزشکی هسته‌ای، دانشکده پزشکی دانشگاه علوم پزشکی و خدمات درمانی تهران، تهران ـ ایران

چکیده

در این پژوهش، یک مدل پویایی‌شناسی سیستم، برای شبیه‌سازی تصمیم‌های مدیریت موجودی مولدهای رادیونوکلید ارایه شده است. در مولدهای رادیونوکلید، رادیودارو به مرور زمان از رادیونوکلید دیگری به نام رادیونوکلید مادر، تولید می‌شود و پس از هر بار استخراج (دوشیدن) رادیوداروی تولید شده، رادیودارو به تناسب مقدار رادیونوکلید مادر باقی‌مانده، تولید می‌شود. وابستگی تولید به زمان، تأثیر متقابل متغیرها، تابع توزیع غیرخطی و بازتولید با توجه به مقدار باقی‌مانده‌ی رادیونوکلید مادر، باعث پیچیدگی فزاینده‌‌ی مدل‌های ریاضی شده و مدل‌سازی را در روش‌های متداول پژوهش در عملیات، مشکل می‌سازد. در مدل ارایه شده، عامل‌های پیش‌گفته مدل شده است و با توجه به ماهیت توسعه‌یابنده‌ی مدل‌های پویایی‌شناسی سیستم و امکان توسعه‌ی مرز مدل، امکان استفاده از مدل به عنوان مدل پایه در مدل‌سازی‌های پیچیده‌تر فراهم شده است. آزمون‌های بازتولید رفتار مدل و شرایط حدی پویایی‌شناسی سیستم، حکایت از اعتبار مدل ارایه شده دارد. در انتها چند سناریو برای افزایش بهره‌وری ارایه شده و بهره‌وری حاصل، به مقدار 25 درصد نسبت به شرایط متداول بهبود یافته است.

کلیدواژه‌ها


عنوان مقاله [English]

A System Dynamics Model for Inventory Decisions in Radionuclide Generators

نویسندگان [English]

  • M Ghadimi 1
  • M. A Shafia 2
  • M. S Pishvaee 2
  • B Fallahi 3
1 School of Industrial Engineering, Iran University of Science and Technology-Tehran-Iran
2 School of Industrial Engineering, Iran University of Science and Technology-Tehran-Iran
3 Research Center for Nuclear Medicine, Dr Shariati Hospital, Tehran University of Medical Sciences,Tehran-Iran
چکیده [English]

A system dynamics model for simulating radionuclide generators inventory management decisions is presented in this research report. The radiopharmaceutical is generated gradually from another radioactive element, so called mother element in the radionuclide generators, and after each extraction of the produced radioactive material, so called elution, the radiopharmaceutical is produced in the proportion of the residue from the mother element. Based on the remained mother element, production time dependence,  mutual interaction of variables, nonlinear distribution function, and reproduction, lead to the incremental complexity of the mathematical model and cause the model making affair harder in common place operation research methods. In the proposed model appeared in this report, the above-mentioned factors are modeled and due to the nature of system dynamics models' development and the possibility of developing the boundary of the model, the feasibility of utilizing the model, as a basic one, in more complex modeling affairs is presented. The model behavior re-production tests and the system dynamics' extreme conditions, illustrate the validity of the proposed model. Ultimately, in this paper, several scenarios for the productivity raise are illustrated and twenty five percent improvement has been shown compared to the conventional models.

کلیدواژه‌ها [English]

  • System Dynamics Model
  • Radiopharmaceutical
  • Radionuclide Generator
  • Technetium-99m

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