عنوان مقاله [English]
نویسنده [English]چکیده [English]
In this paper the effect of sterilization method by gamma-ray on structure and cytotoxicity of polyurethane film surface has been investigated. For this purpose reactive urethane prepolymer was synthesized by the reaction between TDI with a mixture of PEG and Castor oil (50/50, w/w). The cured prepolymer films were prepared due to the reaction of reactive prepolymer with air moisture under ambient conditions. The polyurethane films were sterilized by gamma-ray (25 kGy). The surface structure of sterilized polyurethane film was observed by SEM and compared to that of the unsterilized film. Also, the in vitro interaction of fibroblast L929 cells and sterilized polyurethane film was evaluated. Results showed no signs of cell toxicity.